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Mysimba Approved in the EU

Health Risks of Being Obese

When a person’s body weight is greater than that which is considered healthy for his or her height, that person is considered to be overweight or obese. There are millions of people around that world who are suffering from being overweight or obese. The most common cause of obesity is the lack of energy balance. This simply means that the energy in does not equal to or is less than the energy out. Other causes of obesity include family history, environment, an inactive lifestyle and certain health conditions. Not only is obesity a cosmetic issue, it also puts you at risk for many other health problems including coronary heart disease, high blood pressure, stroke, diabetes and cancer. It is therefore important that people try to live lives that are as healthy as possible so that they do not become obese and that those who are obese find healthy ways of losing weight. 

What is Mysimba? 

Studies have shown that the best way to lose weight is through a reduced-calorie diet and frequent physical activities. There are however certain substances that can enhance the weight loss process when used in combination with a reduced-calorie diet and frequent physical activities. Not all of these substances are healthy and have been approved so it is therefore necessary that you be careful when deciding which of these substances to use. 

 The European Medicines Agency (EMA) has recently given its approval for the marketing of Mysimba to be used in combination with a reduced-calorie diet and frequent physical activity for weight management in adults that are obese or overweight. Mysimba is the new weight loss medication and is a combination of naltrexone and bupropion. It will only be available on a prescription basis to obese adults with a body mass index of 27 kg/m2 or greater and who are suffering from one or more health conditions resulting from them being overweight or obese. The two active ingredients of Mysimba affect two key areas in the brain that are responsible for controlling our body’s food intake and energy expenditure. 

 Not Everyone Approve of the EMA Decision

Although the two active ingredients of Mysimba have already been approved for use in the European Union in other indications, there are many who do not agree with the European Medicines Agency decision. They argue that a weight loss of a few kilograms is not reason enough to justify the exposure of obese or overweight people to adverse effects of the drug, especially based on the fact that most people regain the weight they lose within months of discontinuing the treatment. Other safety concerns related to this drugs are its effects to the central nervous system as well as the cardiovascular system. According to this Orexigen Therapeutics the approval of this drug is a major regression for patient’s safety.

While Mysimba will only be available in the UK after a few months, it is already being marketed in the UK but under the name Contrave. In the US it is definitely considered an option for weight management although according to the safety information, it is said that Contrave can cause its users to have suicidal thoughts. The ingredient in contrive responsible for causing people to become suicidal is bupropion which is one of the main ingredients of Mysimba. For more information on Contrave, you can refer to this BMJ article.

Although not everyone are in support of this medication, some web-based clinics such as this regulated clinic (The Online Clinic) are already gearing up to prescribe this medication. This means that individuals who are looking for that extra boost to help them lose weight in a fast and efficient manner can easily get a prescription online from The Online Clinic and can also easily purchase the medication from the convenience of their home and have it delivered to them.

Get Advice

It is advisable that you talk to your physician before you decide to try Mysimba so that you can get medical advice whether or not you should use this medication. Make sure that you tell the physician about any medical condition that you have or might had had in the past and about any medicine that you are currently taking. This includes any over-the-counter medications, herbal supplements and vitamins. Your physician should be aware of all of it so that the can give you proper advice on whether or not you should use Mysimba. If your physician does not recommend the use of Mysimba, you should not use it because it might have adverse effects on you.


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